Antibacterial Activity of Moringa oleifera Root Bark Extract against Some Pathogenic Organisms
Published: 2020-09-01
Page: 298-304
Issue: 2020 - Volume 3 [Issue 1]
Emmanuel K. Amanze
Department of Microbiology, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Ugonna D. Nwankpa
Department of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Chinedu E. Udekwu
Department of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Henry N. Ogbonna
Department of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Chibuzo V. Nwokafor
Department of Microbiology, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Chukwuma G. Udensi
Department of Microbiology, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Aim: The study is aimed at evaluating the antibacterial activity of Moringa oleifera root bark extract against pathogenic organisms.
Method: The antibacterial activity of methanolic and aqueous extracts of Moringa oleifera root bark was investigated against test organisms (Staphylococcus aureus and Escherichia coli) using agar well diffusion method. Different extracts were prepared at different concentrations (200 mg/ml, 100 mg/ml, 50 mg/ml, 25 mg/ml, 12.5 mg/ml and 6.25 mg/ml).
Results: The methanol extracts showed a higher zone of inhibition than the aqueous extracts at all the extract concentrations and on both test organisms. Also, the observed antibacterial activity was dose-dependent for both extract methods.
Conclusion: The present work showed that Moringa oleifera root bark has antibacterial activity against Staphylococcus aureus and Escherichia coli suggesting its potential as an antibacterial agent against infections caused by the organisms.
Keywords: Antibacterial, Moringa oleifera, pathogenic organisms, plant extracts