Knowledge, Attitude and Uptake of Hepatitis B Vaccine among Clinical Medical Students of a Tertiary Institution in Southeast Nigeria

Main Article Content

N. C. Eze
E. C. Egba
J. E. Ogbanna
S. N. Nwamini
P. U. Nweke
J. S. Amasianya


Background: Hepatitis B virus infection is a global public health problem especially in developing countries like Nigeria. Good knowledge of Hepatitis B virus, its infection and positive attitude by the public are key to the prevention of Hepatitis B infection The infection can be prevented with Hepatitis B virus vaccine. This study aimed at assessing the Knowledge, Attitude and Uptake of Hepatitis B virus vaccine among Clinical Medical Students of Ebonyi State University, Abakaliki.

Materials and Methods: The study is descriptive cross-sectional in design and comprised of 187 Clinical Medical Students selected by consecutive sampling technique. Data was collected using pretested, semi-structured, self-administered questionnaires and analysed using Statistical Package for Social Sciences (SPSS) for Microsoft window version 22.

Results: The mean age of the respondents was 25.6 ± 3.2 years. About 80.7% of the respondents (Clinical Medical Students of EBSU) had good knowledge of HBV infection. Also, all the respondents (100%) had good knowledge of HBV vaccine. Nearly, 74.3% of our respondents were concerned about being infected with HBV. However only 55.6% of them had tested for HBV surface antigen. Also 84.2% of the respondents said they would like to be vaccinated. Although the participants in this study had positive attitude towards HBV vaccination, only 29.4% of the respondents had received HBV vaccine. Most of those vaccinated received incomplete doses of the vaccine while only very few received complete doses of the vaccine.

Conclusions: There should be sustained health education to Clinical Medical Students on the need to be vaccinated against HBV and also HBV vaccine should be made free to the general public so as to remove the challenge created by cost.

Knowledge, attitude, uptake, HB vaccine, clinical medical students, Abakaliki.

Article Details

How to Cite
Eze, N. C., Egba, E. C., Ogbanna, J. E., Nwamini, S. N., Nweke, P. U., & Amasianya, J. S. (2020). Knowledge, Attitude and Uptake of Hepatitis B Vaccine among Clinical Medical Students of a Tertiary Institution in Southeast Nigeria. Asian Journal of Immunology, 4(2), 31-36. Retrieved from
Original Research Article


Alshammari MS, Alshamari NG, Alshammari AS, Kareem M. Electronic Physicians. 2017;(9):5388–94.

Algadheeb AS, Al-alsheikh AS, Al-hamoudi WK, Alswat KA. Medical students’ awareness of and compliance with the hepatitis B vaccine in a tertiary care academic hospital : An epidemiological study. J Infect Public Health 2016;9:60-65.

Bello FM, Health P, Anne CP. Health Workers’ knowledge, attitude and practice towards Hepatitis B Infection in Northern Nigeria. 2017;9(3):939–54.

Mesfin YM, Kibret KT. Assessment of knowledge and practice towards Hepatitis B among Medical and Health Science Students in Haramaya University, Ethiopia. Scientific Research Publishing. 2013; 8(11):1–6.

Reddy RS, Swapna LA, Ramesh T, Pradeep K. Knowledge, attitude and practice on hepatitis B prevention among dental professionals in India. Pan African Medical Journal. 2011;10(4).

Mohammed A, Aldeen Z, Alelyani AM, Alshammari KS, Abdulaziz M, Alsaif B, et al. Assessment of knowledge, attitudes and practices toward prevention of Hepatitis B virus infection among medical students in Hail Region, Saudi Arabia Sky Jounral of Medicine and Medical Sciences. 2017;3(4):31–5.

Taher HA, Mansuri S. Hepatitis B infection control knowledge and practice of undergraduate students at college of dentistry, Madinah, Saudi Arabia. BMC. 2015;3(4):47–51.

Kesieme EB, Uwakwe K, Irekpita E, Dongo A, Bwala KJ, Alegbeleye BJ. Knowledge of Hepatitis B vaccine among operating room personnel in Nigeria and Their Vaccination Status.Hepat Res Treat. 2011;2011:7–12.

Adekanle O, Ndububa DA, Olowookere SA, Ijarotimi O, Ijadunola KT. Knowledge of hepatitis B virus infection, immunization with hepatitis B vaccine, risk perception, and challenges to control hepatitis among Hospital Workers in a Nigerian Tertiary Hospital. Hepat Res Treat. 2015;2015:1–6.

Daboer JC, Chingle MP, Banwat ME. Knowledge, risk perception and vaccination against Hepatitis B infection by Primary Healthcare Workers In Jos, North Central Nigeria. Pan African Medical Journal. 2017;6–10.

Noubiap JJN, Nansseu JRN, Kengne KK, Ndoula ST, Agyingi LA. Occupational exposure to blood, hepatitis B vaccine knowledge and uptake among medical students in Cameroon.Open Access; 2013.

Singh A, Jain S. Prevention of Hepatitis B-knowledge and practices among medical students. BMC. 2012;(2):52–6.

Reang T, Chakraborty T, Sarker M, Tripura A. A study of knowledge and practice regarding Hepatitis B among nursing students attending tertiary care hospitals in Agartala city. International Jurnal of Research in Medical Sciences 2015;3(7): 1641–9.

Abdela A, Woldu B, Haile K, Mathewos B, Deressa T. Assessment of knowledge, attitudes and practices toward prevention of hepatitis B virus infection among students of medicine and health sciences in Northwest Ethiopia. BMC Res Notes. 2016;1–7.

Demsiss W, Seid A, Fiseha T. Hepatitis B and C: Seroprevalence, knowledge, practice and associated factors among medicine and health science students in Northeast Ethiopia. Plos One. 2018;1– 12.

Meriki HD, Tufon KA, Anong DN, Tony J, Kwenti TE, Bolimo AF, et al. Vaccine uptake and immune responses to HBV infection amongst vaccinated and non- vaccinated healthcare workers, household and sexual contacts to chronically infected HBV individuals in the South West Region of BMC. 2018;185:1–18.

Alavian SM, Mahboobi N, Savadrudbari MM, Azar PS, Daneshvar S. Iranian dental students’ knowledge of hepatitis B virus infection and its control practices. World Journal of Vaccines. 2011;12:1627– 34.

Paul N, Peterside O. Hepatitis B Vaccination rate among medical students at the University of Port Harcourt Teaching Hospital (UPTH). World Journal of Vaccines. 2015;(2):1–7.

Papagiannis D, Tsimtsiou Z, Chatzichristodoulou I, Adamopoulou M. Hepatitis B virus vaccination coverage in medical, nursing and paramedical students: BMC. 2015;8(5):1–9.

Fufore MB, Cook PA, Kirfi AM. Health workers’ knowledge, attitude and practice towards hepatitis B infection in Northern Nigeria. International Journal of Caring Sciences. 2016;9(3):939-54.