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Immune systems are responsible for the body’s protection against invading foreign agents that could bring harm to normal cellular activities. Viral infection is one of the significant foreign attacks on the body and the immune system has developed key mechanisms to contain such attack. The recent pandemic of the Coronavirus disease 2019 (COVID-19) has stimulated studies on antiviral response with much emphasis on the Corona viruses. This disease caused by the novel Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-COV-2) has been shown to have evolved with mechanisms to evade the normal immune responses. As such, this review therefore critically apprised recent literature on mechanisms of antiviral responses emphasizing on the Coronaviruses particularly the SARS-COV-2.The paper also highlighted the current situation regarding studies to find cure and vaccine development against the COVID-19.
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