A Pilot Study on Pre-diabetes and Associated Central Obesity among Students of University of Guyana, Guyana

Main Article Content

Dakari Jordan
Dacia Simpson
Rajini Kurup
Audrey Anderson
Cecil Boston


Objective: The purpose of this study was to examine the incidence of pre-diabetes and associated central obesity among sampled University of Guyana students.

Methods: The study was a cross sectional study where a questionnaire was distributed to each participant to assess predisposing risk factors. Anthropometric measurements like BMI and HbA1c were used to ascertain if the participant was overweight or obese. Nycocard® HbA1c test kit was used for collecting HbA1c. Data was analyzed using SPSS 20.0 to calculate descriptive statistics and analysis of variance were used to investigate the research questions. A p value of <0.05 was considered to be significant for all analysis.

Results: A total of seventy-four students were randomly selected for the study. The findings of this study revealed pre-diabetes incidence of 40.5% and a weak positive correlation between central obesity and pre-diabetes, with r-values of 0.25 (males), 0.27 (females) & 0.26 (overall).

Conclusion: There was a weak association between central obesity and pre-diabetes incidence. Therefore, a large follow up study would be important to understand association between pre-diabetes and central obesity and to create nationwide awareness or development of an operational policy/strategy/action plan to reduce overweight.

Incidence, pre-diabetes, central obesity, type 2 diabetes.

Article Details

How to Cite
Jordan, D., Simpson, D., Kurup, R., Anderson, A., & Boston, C. (2020). A Pilot Study on Pre-diabetes and Associated Central Obesity among Students of University of Guyana, Guyana. Asian Journal of Immunology, 3(1), 39-45. Retrieved from https://journalaji.com/index.php/AJI/article/view/30107
Original Research Article


American Diabetes Association. Classification and diagnosis of diabetes: Standards of medical care in diabetes—2020. Diabetes Care 43. Supplement 1. 2020;S14-S31.

Ogurtsova K, da Rocha Fernandes J, Huang Y, Linnenkamp U, Guariguata L, Cho N, et al. IDF diabetes atlas: Global estimates for the prevalence of diabetes for 2015 and 2040. Diabetes Res Clin Pract. 2017;128:40-50.

Tuso P. Prediabetes and lifestyle modification: Time to prevent a preventable disease. Perm J. 2014;18(3):88–93.

Tabak A, Herder C, Rathmann W, Brunner E, Kivimaki M. Prediabetes: A high-risk state for developing diabetes. Lancet. 2012; 379(9833):2279-2290.

World Health Organization. WHO: Obesity and overweight; 2016.

FAO and PAHO. Panorama of food and nutritional security. Healthy food systems to end hunger and malnutrition; 2017.

Ottaviani E, Malagoli D, Franceschi C. The evolution of the adipose tissue: A neglected enigma. General and Comparative Endocrinology. 2011;174(1):1-4.

Esteghamati A, Larijani B, Aghajani MH, Ghaemi F, Kermanchi J, Shahrami A, Ismail-Beigi F. Diabetes in Iran: Prospective analysis from first nationwide diabetes report of National Program for Prevention and Control of Diabetes (NPPCD-2016). Scientific Reports. 2017; 7(1).

Hostalek U. Global epidemiology of prediabetes - Present and future perspectives. Clinical Diabetes and Endocrinology. 2019;5(5).

Zhang P, Wang R, Gao C, Jiang L, Lv X, Song Y, Li B. Prevalence of central obesity among adults with normal BMI and its association with metabolic diseases in Northeast China. PLoS ONE. 2016;11(7).

Mainous AG, Tanner RJ, Jo A, Anton SD. Prevalence of prediabetes and abdominal obesity among healthy-weight adults: 18-year trend. Annals of Family Medicine. 2016;14(4):304–310.

Peltz G, Aguirre MT, Sanderson M, Fadden MK. The role of fat mass index in determining obesity. AM J Hum Biol. 2010; 22(5):639-647.

Yoon KH, Lee JH, Kim JW, Cho JH, Choi YH, Ko SH, et al. Epidemic obesity and type 2 diabetes in Asia. Lancet. 2006;368(9548): 1681–1688.

Coelho M, Oliveira T, Fernandes R. Biochemistry of adipose tissue: An endocrine organ. Arch Med Sci. 2013;9: 191–200.

Nielsen S, Guo ZK, Johnson CM, Hensrud DD, Jensen MD. Splanchnic lipolysis in human obesity. Journal of Clinical Investigation. 2004;113(11):1582–1588.

Garnett SP, Baur LA, Cowell CT. Waist-to-height ratio: A simple option for determining excess central adiposity in young people. International Journal of Obesity. 2008;32(6): 1028–1030.