Asian Journal of Immunology 2019-10-28T07:50:03+00:00 Asian Journal of Immunology Open Journal Systems <p style="text-align: justify;"><strong>Asian Journal of&nbsp;Immunology</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJI/general-guideline-for-authors">Click here for Types of paper</a>) in all aspects of the immune system in all organisms. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> <p style="text-align: justify;"><img src="/public/site/images/sciencedomain/free-sign.gif" width="69" height="28"></p> <p style="text-align: justify;"><strong>Publication Charge: FREE</strong>. All the manuscripts submitted within this month will be published free of cost. There is no publication charge for this month.&nbsp;</p> Assessment of Post Exposure of Benzene on Some Hematology Parameters and DNA Lesions on Adult Wistar Rats 2019-10-22T10:41:46+00:00 Orisadiran Patrick Kunle Adedeji Adebayo Lawrence Adedeji Abiodun Oluwabusola AbdulRahman AbdulFatai <p><strong>Aims:</strong> The study sought to investigate the effect of post-exposure of benzene on some haematology parameters and DNA lesions on adult wistar rats.&nbsp;</p> <p>&nbsp;<strong>Methods:</strong> A total of twenty-eight rats were grouped into 4 groups, with group 1 serving as a control. The remaining 3 groups were interperitoneally administered 0.2 ml of benzene 48 hourly for 4 weeks and were left of 0, 3 and 6 weeks respectively before sacrifice.</p> <p><strong>Results:</strong> The result obtained showed that White Blood Cell (WBC), Red Blood Cell (RBC) and platelet counts were significantly reduced in benzene post exposed groups (p&lt;0.05). 8-hydroxydeoxyguanosine generation in liver and bone marrow were significantly higher in benzene post exposed groups. The photomicrograph of blood film of benzene exposed group showed promyelocyte and myeloblast.</p> <p><strong>Conclusion: </strong>It is concluded that benzene and its metabolite are highly toxic and are potentially damaging agents to the hematopoietic system. Evidence from our study suggested that elevated levels of 8-OHdG in liver and bone marrow compare to control would be a sign of increased oxidative stress, impaired antioxidant defence or inadequate repair of oxidative damaged DNA.</p> 2019-10-22T00:00:00+00:00 ##submission.copyrightStatement## Haematological Assessments of Cocos nucifera Linn. Water and Oil on Apparently Healthy Wistar Albino Rats 2019-10-28T07:50:03+00:00 D. O. Akinjayeju T. T. Adebolu <p>In this study, the effects of the consumption of <em>Cocos nucifera </em>L. water and oil on the haematological parameters of apparently healthy wistar albino rats were investigated using standard methods. The albino rats (n= 100) were divided into 8 groups (A-H) of 12 rats each while the remaining four rats were put in another group to serve as control. The first four groups(A-D) were daily orogastrically administered different volumes of coconut oil, 0.5 ml, 1.0 ml, 1.5 ml, 2.0 ml respectively for 4 weeks while groups E-H were daily orogastrically administered different volumes of coconut water, 0.5 ml, 1.0 ml, 1.5 ml, 2.0 ml respectively for four weeks. The control rats (Group l) however were not administered either coconut water or coconut oil. All the rats were allowed free access to rat chow and water. The administration of either of the coconut water or oil caused a significant increase (p≤0.05) in the PCV, WBC and the differential leukocytes counts within the four weeks of this study with coconut water having higher effect. It is conceivable that the consumption of either coconut water or coconut oil could exert both hematinic and immuno-stimulatory effects in the consumers to checkmate low PCV and also boost innate immunity.</p> 2019-10-28T00:00:00+00:00 ##submission.copyrightStatement##